Individualizing your dosing is always important. Supplementation levels can range from a low of 500 mg to upwards of 15,000 mg (15 grams). When using higher dosing regimens, 3 or 4 divided dosages daily is routinely recommended. With a high dosing regimen, working with a skilled healthcare provider to help you optimize health goals should definitely be a targeted goal when optimizing your body performance goals. Glutamine does not contain gluten and it is different than MSG (monosodium glutamate) or glutamate. Don’t mix glutamine with warm water; tepid or cold water is the way to go.